We hiked in at about 11:00 AM and got to Lake #1 in about 3 hours. There was a guy in an inflatable raft there and within ten minutes we saw him land two fish throwing a fly/bobber.
We continued on the trail and arrived at the far end of Lake #2 in another ten minutes, and by luck stumbled upon this great campsite with no one around.
Shoreline access near our camp was pretty minimal and since I was trying out my new rod/reel combo (7' Okuma Kokanee rod/Quantum baitcaster) I needed a bit more room to cast than if I had my 5'6" Ugly Stik. As a result, I only had about 1/2 an hour to fish that first day, had no strikes, nor saw any surface action. As disheartening as this was, I did see quite a lot of small fry in the water, which was a good sign of this lake's ability to reproduce and had me a bit hopeful of some active fish. Instead we went about the business of setting up camp, including a great lightweight hammock, exploring the area, and eating an early dinner complete with some nice wine.
The evening was clear, crisp/cold for August, stars everywhere and brilliant (something I am constantly amazed at when backpacking even though I live in Sonoma County), and once again realized the folly of bringing my 45 degree bag on a backpacking trip to the Sierras. I got pretty cold that first night, which made sleep a bit difficult.
The next morning we packed our rods/gear and made the 20 minute hike to Lake #5, bypassing the spur trail to #3, and seeing that #4 was choked with grass on the shoreline. We crossed the damn at #5 and hiked along the shore opposite the trail for a few hundred yards to a place that looked like it had a deep drop off. There was ample space to practice casting my new rig, and it went pretty well, although I had more than my share of backlashes when the wind picked up.
Another backlash!

While I was retying my line this "creature" swam right in front of me with a mouse in its mouth, head out of the water. I could see the mouse clearly and the aggressor was brown, maybe a foot in length, with a slender tail. As soon as it came close to me it dove under the water and didn't resurface, though I took a really bad photo of it after it dove under. I looked up marmots when I got home, but they are herbivores from my cursory research. No idea what that thing is. Sorry for the poor vis in the photo...
No fish caught at this lake, but just as was the case at #2, there were fry everywhere in the shallows, and when we were walking back to the outlet creek by the dam, we spotted two large trout (species unknown) swimming in the shallows. From our vantage point above, they looked to be at least 18", but with the distortion that might be much smaller.
After hanging out at this lake for a few hours we walked back to our campsite, my wife climbed into the hammock to read, and I walked to the limited shoreline to continue fishing. Five min after arriving I hooked into a nice fish (always feel that rush when it's the first one on a new rod!), and landed a nice brown that was around 16" on a bead headed nymph.
Five min later I hooked into a bigger one on the same fly, and while trying to land it and take a nice photo this happened:
D-Oh!
Needless to say, my wife and I had a good chuckle at the incident itself, and my expression once we looked at the photo. Following this egregious violation of all standards of trout documentation, the bite completely shut down and I didn't hook another fish for the rest of the trip...
The following day we packed our gear, hiked up towards Phipps pass, and stopped off at Lake #6. I didn't have my gear with me and sure enough there were fish rising in the small, but seemingly deep lake near the summit. Oddly, this was the only lake that I didn't see any fry.
The view from Phipps was pretty amazing. Hard to believe that just over the ridge are hordes of people at Tahoe, depriving themselves of this view:
What I found pretty amazing about this trip in particular was the lack of people we saw on the trail. Neither day hanging out and walking by #5 did we see anyone camped there, and only saw three backpackers that day (perhaps a large amount to those accustomed to solitude on the trail, but scant in my experience in Desolation).
Anyway, we both had a wonderful time exploring this part of Desolation, my wife is a total trooper when it comes to backpacking, and she's even more insistent that we include her fishing rod anytime a lake is near.

Looking forward to more time on the trail later this summer.
Al