I have Kahtoola micro-spikes that work great with my
Altra Lone Peak trail runners. I also have mountaineering boots (
Scarpa Charmoz) & crampons. In my experience, at least from a confidence perspective, trail runners + spikes are roughly equivalent to these (types of) boots alone on anything from flat to maybe 25 degree slopes. Steeper than that, it becomes more of the domain of crampons, ice axe, etc.
As AT mentioned above, by the time you are hiking, there will be well developed tracks across every pass and any sections of trail with remaining snow. Typically, the tracks just follow the actual trail, especially with the advent of GPS devices that indicate where the trail is located underneath. So in those kinds of conditions, trail runners & micro-spikes really excel.
There are different considerations & preferences when to cross passes. For example, Donohue (your first major SOBO pass) will be still holding snow. If you camp south of the bridge, you only have 3 miles to go. Depending on where the snow starts - which you will quickly be able to ascertain from either looking or talking to the many hikers going north - you can determine when to break camp and hit the snow.
I personally like hitting the snow by 6-7am, which means getting up/hiking even earlier depending on the distance to where the snow begins. In the early morning, the snow is still hard & crunchy, so you can move pretty fast. The downside of course is that the snow is still hard & crunchy ie it can be icy & slippery. However, since there will be a boot tracks and trough, you can walk along placing your feet in established compacted steps. If you start later, the snow will be begin to soften and provide more grip, but the downside is you might end up post-holing - especially as you begin to descend the south facing slopes later in the morning.
Since you might have some prior experience with patches along the way, you will develop your own preference as to what type of surface conditions you prefer and let that dictate your subsequent action plans. In any case, I would look into getting calf/knee high gaiters. Not so much to keep snow out of your shoes when (not if) you post hole - even though that's the obvious selling point/benefit - but to protect your shins. If they have a bottom strap, even better, because it might help keep your shoes on when you finally pull your leg/foot out. If you get a full crotch drop, you're looking at digging down 2-3' trying to retrieve a shoe after you extricate yourself.